What? No Tielemans!!!!!!!! Are you mad? Haven't you seen how well he does in training? You can't drop him!
I take it that Soyuncu and KDH are not available? The trouble with those 3 at the back, besides 2 of them 3 being very slow, is that it leaves our central midfield wide open with only Mendy there. And, although I agree that Castagne has been disappointing lately, I'm not sure Pereira is fit enough for the full 90 minutes so we might need a capable sub. Tielemans maybe? We need a tough tackler who's full of energy!
I'd go with 4 at the back and get 3 workers in midfield, leaving one to guard the central defence, to try and win the ball up higher, bin Barnes, and only use him as a substitute if we need him.
While we need a win, we can't afford to give goals away and hope to outscore them, because it won't happen. Try and keep it tight and nick one on the break would do just as well.