St. Malo's a bit of a dump, it's just the closest French port to Jersey! We go to southern Tuscany, that's where my grandparents live. I'd recommend Rome, for obvious reasons, and Assisi.
I've been to Rome, i'd like to see Pisa, and i've never been to Garda and Sorrento, these will be next on the list after the 2 islands.
Pisa i could tie in with a trip to Florence it's only an hours drive or so, but we always get sidetracked, Siena is beautiful as well, so long as you don't mind walking up hills!