So sad to hear about your wife - even though I have been diagnosed CLL the prognosis has changed so much over the last 10 years it gives us hope. Even though we have the antivaxxers - the idea of using MRNA to cure or treat cancers such as CLLis going to provide better and longer lives in years to come.
The first line of treatment with CLL, is watch and wait, if you are lucky and your CLL progresses slowly then you have some chance at life when you do eventually have Cemo, my wife had BR treatment, which she responded to very well and was in remission for 7 years, but she didn't have a long wait and watch initial period, just 11 months, because her CLL was aggressive. When it came back, it came back very aggressive and at the wrong time, when Covid was kicking off and Cancer patients were being sacrificed for this covid pandemic, also the 'Biological' treatments are not the miracle cures they make out, for example, Ibrutinib has been hailed but what they don't tell you is it has a high death rate and is only suitable for 40% of CLL patients, many have to stop taking the drug, also they never tell you that these biological drugs also irreversibly alter your T cells? they also induce Sepsis and Pneumonia, it's a minefield to be honest, and I would recommend 'Health unlocked' (
https://healthunlocked.com/ ).
Of course, most CLL patients die of Pneumonia because of the fact that this cancer attacks the immune system (White cells) so IVIG treatment is critical to staying infection-free, especially if you are starting to get serious infections, but NHS cost control will mean that you either don't get told about this treatment or it's only used once you have had your first hospitalization from Pneumonia, it's a protein anti-body blood fraction treatment derived from blood donations, it's effective for protecting and given regularly, but it depends on the quality of your consultant. All Leukemia is so complicated and while these new Biological treatments are the new treatments there are serious dangers for some, but also a general risk of Pneumonia that is mitigated by the fact that they have to prescribe strong antibiotics alongside the treatments.
Antibiotics of course have their own negative impact on the CLL patient long term, especially the Kidney function, finally, I learned how helpless consultants were to deal with bad reactions to these new biological drugs, spent months watching them totally inept and unable to deal with the complexities of the human body, Doctors now absolutely nothing about the human body, we are still ignorant of the human body's complex systems, God it was only a few months ago that thy found a new gland in the neck, that had gone unnoticed for over 100 years?