Off Topic Coronavirus

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You sure you're OK Stroller? That almost sounded like praise for the government... :grin:
Can't fault them here. Only a week ago people were jumping the gun with the amount of vials we ordered from Pfizer. A fab day for Oxford and our fab scientists.
If people get bored, I am sure The Guardian will be running a story linking a Tory MP to some contract... you know... someone who bumped into someone who knew a mate who met a Tory MP once, so there must be a connection to contracts for mates?
For the rest of us, its a great day for Oxford.
 
Can't fault them here. Only a week ago people were jumping the gun with the amount of vials we ordered from Pfizer. A fab day for Oxford and our fab scientists.
If people get bored, I am sure The Guardian will be running a story linking a Tory MP to some contract... you know... someone who bumped into someone who knew a mate who met a Tory MP once, so there must be a connection to contracts for mates?
For the rest of us, its a great day for Oxford.

If that was the sort of link being exposed constantly you might have a point for once.
 
If that was the sort of link being exposed constantly you might have a point for once.
I always make good points. It's just some can't see past their glasses. Just think the quicker we can roll this out the sooner we can get back to HQ? Just don't test on Norwich fans as growing extra fingers could be seen as normal. :emoticon-0100-smile
 
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I wanted to ask a question about the results from Oxford this morning The CBC and probably several others ran the following quote from Peter Openshaw

Smaller dose may reduce costs
Peter Openshaw, professor of experimental medicine at Imperial College London, said the finding that a smaller initial dose is more effective than a larger one is good news because it may reduce costs and mean more people can be vaccinated.

"The report that an initial half-dose is better than a full dose seems counterintuitive for those of us thinking of vaccines as normal drugs. With drugs, we expect that higher doses have bigger effects, and more side-effects," he said. "But the immune system does not work like that."

Thia is not exactly the same as "they think it gives the immune system more time to get it right". My question then is (I do get there in the end) is that also a load of twaddle? I live in a small city with reasonably good health care options if I have the option, I would rater get a dose that doesn't need -75 deg C storage and lasts longer than 1-3 minutes
 
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So Bawjaws has announced a new tiered system which looks very similar to the tiered system we have up here in Scotland, except we have a Tier 0 and a Tier 4 at the extreme ends of the scale.

Good to know that Covid is planning to take a break over the Christmas period though....whatever happened to the "Don't kill Granny" campaign?
 
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I wanted to ask a question about the results from Oxford this morning The CBC and probably several others ran the following quote from Peter Openshaw

Smaller dose may reduce costs
Peter Openshaw, professor of experimental medicine at Imperial College London, said the finding that a smaller initial dose is more effective than a larger one is good news because it may reduce costs and mean more people can be vaccinated.

"The report that an initial half-dose is better than a full dose seems counterintuitive for those of us thinking of vaccines as normal drugs. With drugs, we expect that higher doses have bigger effects, and more side-effects," he said. "But the immune system does not work like that."

Thia is not exactly the same as "they think it gives the immune system more time to get it right". My question then is (I do get there in the end) is that also a load of twaddle? I live in a small city with reasonably good health care options if I have the option, I would rater get a dose that doesn't need -75 deg C storage and lasts longer than 1-3 minutes


I am not sure we know exactly why this occurs and to be honest the numbers are still small, especially in this secondary arm of low dose then high dose. The theory is that the first doses primes the immune system, the second shot amplifies.
A major advantage is that the 100 million doses ( enough for 50 million people), suddenly becomes enough for 75 million)
The Oxford vaccine looks good...and us practical, cheaper and made in this country.

The best part of the data was even in the 30,% who got Covid...it was mild. They had no severe cases in their cohort... That will do me.

Hope that helps Maple
 
NZ has just agreed to buy 5million single time doses from jannsen pharmaceuticals
Is that a good one


Janssen have just started phase 3 trials in UK on nov16. So a little behind the others...
It has got to phase 3, so probably no health problems...

One of the future
 
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The vaccine uses the same base vaccine that they have used for their successful Ebola virus. Their two jab are 57days apart. So it will take longer to protect you as opposed to the 3 weeks in the Pfizer and Astra/Zeneca-Oxford ones
 
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Am I alone in feeling rather uncomfortable with the Christmas strategy? Open the pubs for a month, then get grandma round for a couple of days in a humid, unventilated house and remember to pass her the sprouts? Shame we couldn’t get the vulnerable jabbed before then. I can’t stop my kids going to the boozer with their mates, and nor would I want to, but we are all getting tested before my Mum arrives. She has been on her own since March and would be completely gutted to spend Christmas alone.
 
Am I alone in feeling rather uncomfortable with the Christmas strategy? Open the pubs for a month, then get grandma round for a couple of days in a humid, unventilated house and remember to pass her the sprouts? Shame we couldn’t get the vulnerable jabbed before then. I can’t stop my kids going to the boozer with their mates, and nor would I want to, but we are all getting tested before my Mum arrives. She has been on her own since March and would be completely gutted to spend Christmas alone.

I'm on the other side of the equation. If anyone is vulnerable it will be me, but I'll have all my kids and grand-kids round.
 
Haven't had either recently. I've begun to wonder if the tiredness might have been connected to the cancer.
Good news. If you were losing weight I could see that the other things would be related to the cancer, but they got it very early, probably symptomless. More likely a persistent bug or light touch of long COVID.
 
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Am I alone in feeling rather uncomfortable with the Christmas strategy? Open the pubs for a month, then get grandma round for a couple of days in a humid, unventilated house and remember to pass her the sprouts? Shame we couldn’t get the vulnerable jabbed before then. I can’t stop my kids going to the boozer with their mates, and nor would I want to, but we are all getting tested before my Mum arrives. She has been on her own since March and would be completely gutted to spend Christmas alone.

Very few pubs will be open. London pubs in Tier 2 say they'll go bust and most of the country will be Tier 2 or above. The government just seem to be over-cautious with that and football but a big mix over Christmas will surely result in a massive rise in cases in January which is normally the worst month for Flu. A perfect storm...
 
Good news. If you were losing weight I could see that the other things would be related to the cancer, but they got it very early, probably symptomless. More likely a persistent bug or light touch of long COVID.

I had a bit of a knock-back on the cancer front. After the positive meeting last Tuesday, I got a call on Friday to say that the multidisciplinary meeting had concluded that their recommendation was that I should have the offending part of my colon removed, which would involve having a colostomy bag. I've got another meeting with the consultant next Tuesday to find out more, but I might decline.
 
Am I alone in feeling rather uncomfortable with the Christmas strategy? Open the pubs for a month, then get grandma round for a couple of days in a humid, unventilated house and remember to pass her the sprouts? Shame we couldn’t get the vulnerable jabbed before then. I can’t stop my kids going to the boozer with their mates, and nor would I want to, but we are all getting tested before my Mum arrives. She has been on her own since March and would be completely gutted to spend Christmas alone.

It's a licence for chaos - idiots everywhere will inbore the guidance, putting countless lives at risk if the vaccine isn't rolled out in time for the most vulnerable out there. The government have bottled it on this - and when the cases sky-rocket in January it'll be the public that get the blame for this for not acting sensibly.
 
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