Swansea City will kick-off the 2021-22 Championship season with a trip to Lancashire to take on Blackburn Rovers at Ewood Park on Saturday, August 7.
It will be the first time the clubs have met on the opening day of a league campaign since the 1956-57 season, when the Swans emerged 5-1 winners at the Vetch.
The Swans will be searching for a first win at Ewood Park in 50 years, having drawn all three of their fixtures at the ground since returning to the Championship in 2018.
Swansea have enjoyed a fine record in opening fixtures over recent years, last losing the first game of a league season in 2013 against Manchester United.
The two South Wales derbies are set for October 16 and April 2, with the first of those taking place at the Liberty Stadium.