Buendia will be a miss - but we said the same when Klose was out, then again for Leitner, Pukki, Vrancic... Each time the replacement has risen to the challenge.
Interesting conundrum for Farke as to who comes in. Vrancic was the most recent performer who lost his spot due to a knock, but Leitner had that spot locked down earlier in the season.
Either comes with the assumption that you move McLean wide, thus breaking up a midfield duo which has won 8 games in a row! So does Cantrell come in, to minimise disruption?
I'd go for Vrancic personally, but trust Farke!