I think and hope MH will stick to the same formation now he's found out what works, and makes as few changes as possible. For me that means Betty for BZ and Smith, I'd prefer over SWP now, for Mackie in the same roles.
Yes, Mackie got a whackie near his crackie, but the club quackie said it ain't enough to put him on his backie.
Hughes will hopefully gameplan for this like he has done against Arsenal and Swansea. However if I was to pick the team and those two were out, i'd put Derry in the middle instead of Buz, and then play Buz, Adel and DJ as a sort of free flowing front 3. Choosing to play Bothroyd or SWP (or god forbid both) is like starting with 10 men
Personally, I'd stick with Bothroyd if Helgusson ain't ready to come back (which seems to be the case). The Rs need some height up front. I think Mackie will be back.